NURSING 2LA2 Lecture Notes - Lecture 1: Glycogenolysis, Hyperglycemia, Corticosteroid

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3 components of stress: external stimuli, individual judgment & the physiological response. Quantity: identifies negative consequences of stress from an accumulation of stressors (positive or negative) in too short of time. Quality: major change: affects large # of pp. ex. War: major change: affects few pp. ex. Divorce: daily hassles: normal people with normal lives experience. Changes that follow divorce: chronic intermittent ex. Stress is a persons conscious appraisal that a disturbance has occurred challenges persons ability to cope. Therefore ppl are not passive victims of stress. Frustration) leads to hormonal response: mediated response. Catecholamine"s (epinephrine, norepinephrine, dopamine: potential consequences= positive and negative. *cortisol is secreted during periods of stress and essential for survival. Increases blood glucose (by decreasing peripheral uptake and increasing gluconeogenesis) & decreases insulin sensitivity. Anti-inflammatory effect: increases autoimmune responses, increases humural immunity (increases t- helper 2 cells, t-helper 1 supressed by cortisol= imbalance called t helper 2 shift)

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