PSYCH 2AP3 Lecture 27: Lecture 27 - Schizophrenia

• School: McMaster University
• Department: Psychology
• Course: PSYCH 2AP3
• Professor: Richard B Day

Document Summary

Impaired interpersonal functioning: social withdrawal, emotional detachment, psychomotor behavior (catatonia), stupor: cerea flexibilitas", excitement. Symptom frequency: lack of insight 94, blunted affect 82, asociality 79, delusions 73, autistic behaviour 72, apathy 60, thought derailment 58, suspiciousness 51% Positive vs negative symptoms: positive symptoms, disturbance, excess of normal function, hallucinations, delusions, negative symptoms, diminution, loss of normal function, alogia: poverty of speech, flat affect, anhedonia asociality, avolition. Course of schizophrenia: one episode, full remission: 25% of cases, episodic, partial remission: 25% of cases, episodic, full remission: 20% of cases, episodic, becoming chronic: 15% of cases, chronic deterioration: 15% of cases. Epidemiology: point prevalence, us & canada: 50-70/10,000, lifetime prevalence, us & canada: 100-190/10,000, us & canada: 150/10,000, onset in adolescence, early adulthood, usually diagnosed 18-35 years, more males than females, 1. 0/1. 0 2. 0/1. 0 male female ratio. Glutamate hypothesis: could be glutamate receptors responsible, refer back to glutamate in depression, problems, glutamate receptors all over the place responsible for excitatory responses.