BIOL 200 Lecture Notes - Lecture 4: Sphingosine, Alkanolamine, Fluid Mosaic Model
24 Jan 2018
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Membranes (part 1): lipid components: structure comes from chemistry, all cells have a membrane (defining characteristic, eukaryotic have internal membranes unlike bacterial cell. Jobs of the membrane: cell membrane = plasma membrane, selective permeability: membrane allows some things to go in/out; structures associated with this; regulation important (remove waste, take in nutrients, communicating with other cells about outside environment (import/export) Lipids: structural building blocks of cellular membranes: biological lipids, hydropho(cid:271)i(cid:272) (cid:373)ole(cid:272)ules (cid:894)(cid:271)iologi(cid:272)al def"(cid:374)(cid:895, dissolve in (cid:374)o(cid:374)polar solve(cid:374)ts (cid:894)(cid:272)he(cid:373)i(cid:272)al def"(cid:374)(cid:895, ex. oils, fats, waxes. Important class of lipids includes fatty acids (subcategory of biological lipids), most common: hydrocarbon chain (squiggly line, carboxylic acid: function group, see far right, side note: carbons like to make 4 covalent bonds. Includes phospholipids, sphingolipids, cholesterol, glycolipids: phospholipids (found mostly in cell membranes, contain glycerol backbone, 2 acyl groups (fatty acids) at c1 and c2. Acyl groups can be different from each other: phosphate in head group.
