NSCI 323 Lecture Notes - Lecture 6: Chemical Synapse, Ganglionic Eminence, Development Of The Human Cortex
30 Sep 2017
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Corticogenesis regression"s slope measures the additional proportion of cells that entered s phase during the 2 hr interval following injection - it indicates the rate of the cell division cycle: The time it takes for all cells to be labeled (p=1) is equal to the cycle"s duration of the last cells that entered cell phase. Rate of cell division cycle; reciprocal = duration of the cell cycle. If you inject brdu after s, you have to wait till the cell undergoes the cycle fully before you see the labeled. Conclusion -> despite the longer cell cycles, we have more rounds of cell division elapse during the neurogenetic period in monkeys than in rodents. Basket and chandelier cells express pv and contact pyramidal cells" proximal dendrite, soma, and axon initial segment. Martinotti cells express somatostatin and contact layer-i tuft dendrites (distal) of pyramidal cells.
