BCHM 102 Lecture Notes - Lecture 13: Lingual Lipase, Atherosclerosis, Amphiphile
2 Dec 2016
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Document Summary
In membranes, as droplets in adipocytes, or associated with proteins in the blood. Structural component of cell membranes: major source of energy, may serve as fat-soluble vitamins. Structural component of prostaglandins and steroid hormones: deficiencies and imbalances of lipid metabolism lead to diseases such as atherosclerosis, diabetes, and obesity. Dietary lipids: dietary lipid intake for an adult is 60-150 g/day. 10 % cholesterol, cholesterol esters (ce), phospholipid (pl) and unesterified (free) fatty acids. Involves enzymes produced in: mouth, gastric cells, and pancreas. Lingual lipase released from glands behind the tongue: gastric lipase released from mucosal cells lining the stomach, degrade short/med length tags to glycerol and free fatty acids. Particularly important for lipid digestion in infants where milk fat (high in tags) is the primary source of energy. Also important in cystic fibrosis patients who have pancreatic insufficiency. Cf is most common lethal genetic disease in caucasians of northern european decent.
