BIOL 102 Lecture 3: BIOL102 Boag Lecture #3 Population Genetics and Causes of Microevolution

32 views3 pages

ultramarinemanatee846

14 Feb 2017

School

Department

Course

Professor

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

(cid:373)utatio(cid:374) does(cid:374)"t (cid:396)e(cid:449)all(cid:455) cha(cid:374)ge allele f(cid:396)e(cid:395)ue(cid:374)c(cid:455) to a sig(cid:374)ifica(cid:374)t e(cid:454)te(cid:374)t. Expectation of allele frequency from one generation to the next. Iclicker: for h w equilibrium to obtain, which of the following conditions must not be true: populations are very large, individuals mate at random, genotypes vary in fitness selection! That natural selection is favoring one genotype at the expense of other genotypes. H-w assumes equal genotypes: immigration and emigration are zero, mutation is rare or absent. All the other assumption are necessary for hw equilibrium to occur. Knowing p and q can use binomial expansion to find genotype frequencies. At any given locus has two different alleles modeling sexual reproduction (two homologous chromosomes at the homologous loci. Two same homozygous (product of individual probabilities p2 or q2, two different heterozygous (2pq) 42% heterozygotes will produce alleles that are 70% a and 30% a. Pool of sperm and eggs with 70% a, 30%a.

Related Questions

Need help with evolution questions:

1.) A haplotype is best defined as the ________________.

	haploid genotypes of all the gametes produced by a diploid individual

ABO blood type conferred by an individual gamete

genotype of either the paternal or maternal chromosomal complement

multilocus genotype of a chromosome or gamete

2.) Which of the following statements regarding linkage disequilibrium is true?

Exists when D is less than zero, but not when it is greater than zero.

Is reduced by sexual reproduction.

Is increased by crossing-over during meiosis.

Is increased by any random sampling error that happens to create or destroy certain chromosome genotypes but not others.

Is reduced by selection that favors certain combinations of genotypes.

3.) Selection on multilocus genotypes in random-mating populations leads to linkage disequilibrium when _______________.

it reduces mutation rates

it eliminates all haplotypes from the population

it prevents crossing-over during meiosis

some allele combinations confer greater fitness than do others

4.) When two loci are in linkage equilibrium, the allele carried on a chromosome at one locus is independent of the allele carried on the chromosome at another locus. When this is the case, _________________.

allele frequencies will not change over time

the two loci (or, more specifically, their protein products) do not interact

the frequency of each haplotype can be calculated by multiplying the frequency of its two alleles

all possible haplotypes occur at equal frequency

5.) Which of the following accurately characterize(s) Muller's ratchet model for the selective advantage of sexual reproduction?

Drift establishes linkage disequilibrium because multilocus genotypes with few mutations are eliminated by chance events.

In populations without sexual reproduction, deleterious mutations accumulate, eventually imposing such a burden that the population goes extinct.

Sex is favored selectively because it recreates the zero-mutation genotypes lost due to drift.

All of the above correctly characterize Muller's ratchet model for the evolution of sexual reproduction.

6.) The genetic signature of recent positive selection on a locus is _______________.

high frequency and low linkage disequilibrium

low frequency and low linkage disequilibrium

low frequency and high linkage disequilibrium

high frequency and high linkage disequilibrium

7.) Sexual reproduction is advantageous both in changing environments and in constant environments, compared to asexual reproduction.

True

False

8.) Sexual reproduction causes genetic recombination via crossing-over, which combines genotypes from different parents.

True

False

9.) One reason sex may be maintained in natural populations is proposed by the "Red Queen Hypothesis", which states that.....

genotypes created by sex are created by natural selection over and over

recombination creating novel genotypes that can resist infection by parasites

mutation load is reduced by novel adaptive mutations

the ability of sex to fix multiple

1.. Polymorphisms for a given trait are relatively common in most species. Discuss the possible advantages or polymorphisms in terms of evolutionary fitness. Be sure to relate your discussion to a specific example. It is also possible that organisms showing more heterozygosity may actually be less fit. Describe one such possible scenario.

2. In the peppered moth (Biston betularia), black individuals may be either homozygous (A1A1) or heterozygous(A1A2), whereas the pale gray moths are homozygous (A2A2). Suppose that in a sample of 250 moths from one locality, 108 are black, and 142 are gray.

3. Retrace the history of primate evolution from early primates to monkeys, apes and hominins. When did some ofthe significant divergences occur (such as between the prosimians and the monkeys or between the chimps and hominins)? What was happening with the continents and the major climatic conditions during these times?What are the major species (including the extinct species) along the human lineage after the split with the chimps and bonobos? Where did many of these events occur on the globe and when?

4. Spencer Wells described his study how the genetic markers in humans are being used to infer the historical geographical distribution of humans and the dispersal of our ancestors. Explain how the genetic markers on our DNA (from blood samples) helps us understand that history. What are the techniques he is using? What is the nature of the evidence? What are the major conclusions about the journey of our ancestors out of Africa?What were the major migrations of humans to all the other continents? Approximately when did each migration occur and what were the major paths? How does the evidence support these conclusions? What Supporting evidence besides the DNA evidence is being used to support these conclusions?

5. Provide an adaptive and a non adaptive hypothesis for the evolutionary loss of useless organs, such as eyes in many cave-dwelling animals. How might these hypotheses be tested?

6. Directional selection is one of the models of natural selection. Describe this type of selection in terms of the frequencies of advantageous alleles over time. What is the trend over time? What is the eventual outcome for this allele as long as no other evolutionary factors intervene? Describe at least one good example of directional selection.

7. Consider the first copy of an allele for insecticide resistance that arises by mutation in a population of insects exposed to an insecticide. Is this mutation an adaptation? If, after some generations, we find that most of the population is resistant, is the resistance an adaptation? If we discover genetic variation for insecticide resistance in a population that has had no experience of insecticides, is that variation an adaptation? If an insect population is polymorphic for two alleles, each of which confers resistance against one of two pesticides that are alternately applied, is that variation an adaptation? Or is each of the two resistance traits an adaptation?Explain your reasoning thoroughly.

8. Suppose that a mutation in a species of annual plant increases allocation to chemical defenses against herbivores, but decreases production of flowers and seeds (i.e., there is an allocation trade-off). What would you have to measure in a field study in order to predict whether or not the frequency of the mutation will increase?

9. In many socially monogamous species of parrots and other birds, both sexes are brilliantly colored or highly ornamented. Is sexual selection likely to be responsible for the coloration and ornaments of both sexes? How can there be sexual selection in pair-bonding species with a 1:1 sex ratio, since every individual presumably obtains a mate? Which of the models of sexual selection described in the book might account for these species characteristics?

10. Kin selection explains why organisms may provide benefits to relatives. Is there a conflict between the principle of kin selection and the evolution of siblicide and abortion?

11.Many species of albatrosses and other seabirds nest in colonies on islands. The adult search for food at sea,sometimes over great distances. Some ecologists who study seabirds turn to their favorite topic of discussion in a bar one evening, and one says, âI can imagine an albatross genotype that destroys the eggs of nestlings of its colony mates when the parents are away foraging, and leaves them dead without eating them. Do you think such a behavior would evolve?â One of his companions says, âYes, because it would make more food available for the albatross and its offspring.â Another says, âNo, because it would threaten the survival of the population.â The fourth says, âYouâre both wrong. I have a different explanation for why albatrosses donât kill othersâ chicks.â What is the fourth ecologistâs explanation, and why does she think her companions are wrong?

12. The concept of a species is fundamental to understanding biology, yet there may not be one definition that fits all âtypesâ of organisms (e.g. animals, plants, fungi, bacteria, slime mold, lichens, etc.). Discuss several of the definitions of a species as presented in class and present your own definition for a species. Compare the strengths and weaknesses of each definition. Ernst Mayr is strong proponent of the biological species concept.How does he justify his position? Do you agree or disagree? If we employ the biological species concept, when did species first exist? What were organisms before then, if not species? What might the consequences of the emergence of species be for processes of adaptation and diversification? Be sure to explain your reasoning thoroughly.

13. The process of speciation ultimately involves the development of reproductive isolation between two related populations of organisms. Describe the various types of both prezygotic and postzygotic reproductive isolation and give an example of each.

14. Respond to the following quote from the character named Mr. Spock in âStar Trekâ:âA truly successful parasite is commensal, living in amity with its host, or even giving it positive advantages, as for instance, the protozoans who live in the digestive system of your termites and digest for them the wood they eat. A parasite that regularly and inevitably kills its host cannot survive long, in the evolutionary sense, unless it multiplies with tremendous rapidity ... it is not pro-survival.âFrom what you have learned in this course, do you agree or disagree with Spock? How can you apply your reasoning to the relative âfitnessâ of HIV which causes AIDS, the Ebola virus which causes hemorrhagic fever,fleas which suck blood from dogs, or the prokaryotic ancestors of mitochondria and chloroplasts?

15. In many species of birds and mammals, clutch size is larger in populations at high latitudes than in population sat low latitudes. Species of lizards and snakes at high latitudes often have smaller clutches, however, and are more frequently viviparous (bear live young rather than laying eggs), than low-latitude species. What selective factors might be responsible for these patterns? Explain your reasoning.

16. The popular media often presents evolution as being a predictable process with a definite goal. For instance, in one âStar Trek: Voyagerâ episode, the captain instructs the shipâs computer to extrapolate the âprobable courseâ of evolution of hadrosaurs (a bipedal dinosaur), if hadrosaurs had been removed from Earth before the Cretaceous-Tertiary (K-T) Extinction and allowed to evolve on another planet. What information about the hadrosaursâ new environment would have been useful in developing the best possible prediction? Given what you know on genetic drift and selective agents, is it possible to accurately predict the long-term course of evolution?

17. Young children often develop strong food preferences that sometimes seem bizarre to their parents --- such as wanting to eat only a certain food prepared in a familiar way, or being reluctant to each new foods or foods with strong or bitter tastes (like coffee and some vegetables). Develop an evolutionary explanation for such preferences. What evidence would you gather to investigate your hypothesis and rule out alternative explanations?

18. Many organisms, such as mammals, only reproduce by sexual means. Other organisms are exclusively asexual,such as many of the bacteria and fungi. And still others have ways of propagating by both sexual and asexualmeans. Discuss the relative advantages and disadvantages of each mode of reproduction. Why arenât all organisms sexual critters? Why are many asexual organisms still very successful as evidenced by the pure abundance and diversity? What is the adaptive significance of having different genders (e.g. male and female)?In other words, why sex?

19. How might differential expression and regulation by Hox genes contribute to mosaic evolution in which different segments of an animal body plan evolve different morphology?

20. Development of a morphological structure involves many different types of gene products, including transcription factors, signaling proteins, and âeffectorâ genes such as enzymes. When a morphological change occurs in a single mutational step, which of these types might be more or less likely to be involved? Within a gene, would such single-step events be more likely to involve coding or non-coding sequences, and what characteristics of the geneâs function might affect this likelihood?

21. Since 2001, the complete DNA sequences of the genomes of many people have been determined. If humans,along with other forms of life, have evolved from a common ancestor, what evidence of this would be expected in the human genome? In what ways might the history and processes of evolution help us interpret and make sense of the human genome sequence data?

22. Paleontologists and some biologists commonly infer function, and even behavior, from anatomical details.Skeletal features, for example, are often used to infer that an extinct mammal (such as an early hominid) was highly, somewhat, or not at all arboreal. This inference assumes a good fit of form to function (i.e., optimal form). Can this assumption be justified?

23. Stephen Jay Gould (1989) and others have argued that the evolution of self-conscious, intelligent species (i.e.humans) was historically contingent: it would not have occurred had any of a great many historical events been different. The philosopher Daniel Dennett (1995) and others have disagreed, arguing that convergent evolution is so common that if humans had not evolved, some other lineage would probably have given rise to a species with similar mental abilities. What do you think, and why? If Gouldâs position is right, what are its philosophical implications, if any?

24. Explain how Intelligent Design was determined as a religious view rather than a scientific view in the court casein Dover, PA. Should a scientific explanation of evolution be included in a science curriculum in K-12 schools?How is science and religion different in how they seek answers to questions? How is term "theory" used differently in science than in everyday English use? What is biological evolution? What evidence is used to support the scientific explanation of evolution? Is it possible to accept scientific explanations without rejecting religious faith?

25. Discuss how a creationist versus an evolutionary biologist might explain some human characteristics and the implications of their differences. Sample characteristics: eyes; wisdom teeth; individually unique friction ridges(fingerprints); five digits rather than some other number; susceptibility to infections; fever when infected;variation in sexual orientation; limited life span.

If an organismâs diploid chromosome number is 18, how many different possible combinations of homologous chromosomes lining up during meiosis exist for the eggs or sperm produced by that organism?

	A.	512
	B.	9
	C.	18
	D.	128
	E.	36

At the end of metaphase I, _______________ separate.

	A.	sister chromatids
	B.	germ cells
	C.	homologous chromosomes
	D.	haploid chromatids
	E.	centrioles

Mendel observed that dominant traits

	A.	are seen in all of the F1 hybrid pea plants in his experiments.
	B.	are expressed in all plants.
	C.	were absent in the F1 generation of pea plants that he used in his experiments.
	D.	were the only traits seen in the F2 generation of pea plants in his experiments.
	E.	are only expressed in hybrids.

Cytokinesis in plant cells differs from cytokinesis in animal cells because

	A.	there is no difference.
	B.	in plant cells, the cell plate must also divide into two parts.
	C.	the contractile protein, actin, is important only in plant cells.
	D.	plant cells have a rigid cell wall.
	E.	a contractile ring forms only in plant cells.

Sickle cell anemia is an example of what type of inheritance?

	A.	complete dominance
	B.	incomplete dominance
	C.	codominance
	D.	multiple alleles
	E.	recessive dominance

Which of the following statements is true:

	A.	The dominant allele is masked in homozygous dominant individuals.
	B.	With recessive genetic disorders, if both parents are carriers, the offspring will all be affected.
	C.	In carriers, the recessive allele causes an intermediate phenotype.
	D.	In recessive genetic disorders, the mother and/or father of an affected individual must also be affected.
	E.	With dominant genetic disorders, the mother and/or father of an affected individual must also be affected.

Skin cancers typically develop in the

	A.	upper layers of the epidermis.
	B.	lower layers of the dermis.
	C.	subcutaneous layer.
	D.	lower layers of the epidermis.
	E.	upper layers of the dermis.

Duchenne muscular dystrophy (MD) is inherited from an X-linked recessive allele. What is the probability that a son with Duchenne MD inherited this disease from his biological father?

	A.	1/2
	B.	0
	C.	1/16
	D.	1/4
	E.	1/8

The genetic makeup of a particular trait in an individual is its

	A.	genotype.
	B.	heterozygosity.
	C.	phenotype.
	D.	filial.
	E.	dominance.

What structure holds the sister chromatids to the spindle fibers?

	A.	chromatin
	B.	kinetochore
	C.	MPF
	D.	centromere
	E.	cyclin

If you view a cell in which the genetic material is beginning to be visible as separate bodies, and the nucleus has disappeared from view, you may surmise that the cells is in

	A.	telophase.
	B.	anaphase.
	C.	interphase.
	D.	metaphase.
	E.	prophase.

Gregor Mendel was successful in his analysis of the genetics of pea plants because

	A.	he examined and analyzed both the F1 and F2 generations.
	B.	he studied the parental plants to determine their differences.
	C.	he decided to only look at his results in an objective manner.
	D.	he studied a trait that had a strange inheritance pattern.
	E.	pea plants have genetics different from other organisms.

Tall corn plants (T) are dominant to dwarf plants (tt). Solid green leaves (G) are dominant to leaves with a white tip (gg). A cross between two corn plants yielded the following phenotypes: 51 tall plants with a white tip on their leaves; 43 dwarf plants with solid leaves; 48 dwarf plants with white tips on their leaves; 45 tall plants with solid leaves. What are the genotypes of the parents that produced these plants?

	A.	None of the above
	B.	TtGg x Ttgg
	C.	ttGG x TTgg
	D.	TtGg x TtGg
	E.	TtGg x ttgg

In humans, a gene that has been identified as causing a type of skin cancer is the

	A.	superwoman echidna.
	B.	mutant superman.
	C.	sonic hedgehog.
	D.	mutant mole rat.
	E.	superhero aardvark.

The segregation principle states that in sexually reproducing diploid organisms the two copies of each gene

	A.	segregate from each other during meiosis.
	B.	must always be the same allele.
	C.	separate from each other during mitosis.
	D.	will both wind up in either the sperm or egg.
	E.	move together as a unit during meiosis.

In what phases is the genetic material in the cell correctly referred to as chromatids?

	A.	metaphase and telophase
	B.	anaphase and metaphase
	C.	interphase and telophase
	D.	interphase and prophase
	E.	metaphase and prophase

Consider two traits for an organism, determined by two genes, each of which is governed by at least two alleles. In the case of a dihybrid individual, the gametes formed will be of either the parental type or the recombinant type. Recombinant type gametes are formed because of

	A.	the principle of dihybrids.
	B.	multiple alleles.
	C.	heterozygosity.
	D.	incomplete dominance.
	E.	independent assortment.

An allele is

	A.	an alternate form of a gene.
	B.	always recessive.
	C.	the main factor determining a trait.
	D.	always one of a pair.
	E.	the dominant form of a gene.

After the DNA is replicated, and it condenses in prophase, two identical rods of DNA are seen. These are

	A.	spindle fibers.
	B.	kinetochores.
	C.	chromatids.
	D.	chromatin.
	E.	centromeres.

Special cells found in the gonads that give rise to gametes upon division are called

	A.	egg cells.
	B.	somatic cells.
	C.	germ cells.
	D.	stem cells.
	E.	basal cells.

BIOL 102 Lecture 3: BIOL102 Boag Lecture #3 Population Genetics and Causes of Microevolution

Document Summary

Get access

Related Documents

BIOL 102 Chapter Notes - Chapter 14: Dihybrid Cross, Mutual Exclusivity, Mendelian Inheritance

BIOL 102 Lecture Notes - Lecture 15: Pea, Pisum, Zygosity

BIOL 102 Chapter Notes - Chapter 15: Homologous Chromosome, Xist (Gene), Barr Body

Related Questions