CHEM 282 Lecture Notes - Lecture 19: Leaving Group, Alcohol, Electronegativity

• School: Queen's University
• Department: Chemistry
• Course: CHEM 282
• Professor: John Carran

Document Summary

Electrons from electronegative atom attract the hydrogen; the electrons that were initially holding hydrogen become part of the double bond. The zaitsev s rule is associated with e2? elimination. With this rule, the more substituted alkene is the more stable and dominates. Oh is a good leaving group only if it is protonated. To keep it protonated, a strong and concentrated acid can be used. If it is a good base, it is probably a horrible leaving group. The dehydration mechanism is a useful e1 mechanism. Hydroxyl is protonated - this makes it a good leaving group. The substrate may be a secondary or tertiary alcohol. The formation of the carbocation is the slowest step. Carbocations can rearrange if possible to form a more stable carbocation. Good to use a solvent that solvates carbocations. The acid is regenerated in the final step.