MICR 221 Lecture Notes - Lecture 7: Cell Membrane, Electron Transport Chain, Fluid Mosaic Model

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Lipids and proteins: lipids lack sterols (except mycoplasma, peripheral and integral proteins. Retains cytoplasm selective permeability barrier transport systems respiration, energy generation chemotaxis: membrane and wall synthesis photosynthesis. Substrate level phosphorylation: atp synthesized from adp by phosphorylation coupled with breakdown of a high energy organic substrate. Variety of pathways to catabolize glucose: e. g. glycolysis usually results in glucose-------> pyruvate with some atp, much more atp generated when pyruvate is converted to co2 via tca cycle. Tca cycle generates nadh and fadh2: most atp generated from electrons of nadh and fadh2 passing through etc. Chemiosmotic theory: as electrons are passed down the respiratory chain, the energy released is used to pump h+ across the cm creates a ph and a charge gradient, protonmotive force (pmf) Cm impermeable to h: once pmf set up the gradients are used for work. Large substrates: macromolecules (starch, cellulose) are too large degraded by extracellular enzymes such as amylases and cellulases converted to smaller transportable units.

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