PHAR 100 Lecture Notes - Lecture 1: Shennong, Ebers Papyrus, Papaver Somniferum

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Illustrate the path of a drug from when it enters to when it exits the body. 4: explain how and why adverse drug reactions and drug-drug interactions occur. Section 01: history of drug use and development. Humans have used drugs since before recorded history. Early written records from egypt and china give us a glimpse of the ancient traditions of drug use. Useful drugs such as opium was identified over 2000 years ago, but the majority of useful clinical drugs have been developed over the past 250 years with the advent of the experimental biological sciences including pharmacology. In the year of 380 b. c. , in ancient greece, theophrastus, a pupil of aristotle, wrote a textbook on therapeutics that included opium. Opium is obtained from the opium poppy (papaver somniferum. ) Serturner, a pharmacist working in germany in 1803, isolated crystals of morphine from opium and tested the pure substance on himself and three companions, discovering its pain relief capabilities.

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