BCH 261 Lecture 2: Biochem Notes 2

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Pure water carries electrical current as h3o+ migrates towards the cathode and oh- towards the anode. Weak acid: partially dissociates/donates a h+ and weak base: partially ionized to accept h+ Buffers are aqueous systems that tend to resist changes in ph when small amounts of acid or base are added. A buffer is consisted of a weak acid and its conjugate base. Overall effect is that a buffer can replace or remove h+ that are either consumed or added to the buffer solution. Multiprotic acids have multiple pka and buffer zones (acids with more than 1 hydrogen)- amino acids. The isoelectronic point is the ph at which the amino acid does not migrate in an electric field. This means it is the ph at which the amino acid is neutral (no net charge) Intracellular ph is 7. 2, blood ph is 7. 4.

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