BLG 10A/B Lecture Notes - Lecture 27: Sister Chromatids, Anterior Pituitary, Activin And Inhibin

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Sperm in males: ova (eggs) in females, combine genetic info through fertilization. Zygote: fused sperm & egg, the primary cell of a living organism. Support development of fetus during gestation & birth parturition. Produce gametes & sex/steroid hormones: gametes formed by meiosis. Testosterone in males, estrogen & progesterone in females: vital in development & function, sexual behaviour & drives. Production of gametes involves hormones (gnrh, fsh, lh, testosterone, & inhibin) Sex hormones exert neg feedback on hypothalamus & anterior pituitary. Inhibin is released from gonads, exerts neg feedback on fsh from anterior pituitary. Puberty: when reproductive organs grow to adult size & become functional. Earliest time that reproduction is possible: hypothalamus becomes less sensitive to inhibin, release gnrh in pulses. Before puberty, low levels of steroidal sex hormones supress secretion of gnrh. Meiosis: unique nuclear division that only occurs in gonads. Reduces # of chromosomes in gametes by half. Each chromosome has 2 identical sister chromatids joined by centromeres.

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