BLG 143 Lecture Notes - Lecture 4: Thymine, Adenine, Nucleoside Triphosphate

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30 Sep 2016
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Nucleic acids are polymers; made up of monomers called nucleotides. A nucleotide has three parts: phosphate group o. Ribose: has an oh (hydroxyl group) on carbon 2 (ribonucleotides polymerize to form rna) Deoxyribose: has an h on carbon 2 (deoxyribonucleotides polymerize to form dna: nitrogenous base. Uracil is found in rna; thymine is found in dna. The phosphate is bonded to the sugar molecule which is bonded to the nitrogenous base. Primary structure of nucleic acids - sequences of any four nitrogenous bases extend from the sugar-phosphate backbone. Nucleic acids form when nucleotides polymerize: condensation reaction forms a phosphodiester linkage between the phosphate group of carbon 5 of one nucleotide and the oh group on carbon 3 of the other nucleotide o. If the nucleotide backbone has a ribose as the sugar, then the polymer is a ribonucleic acid (rna) o. If the nucleotide backbone has a deoxyribose as the sugar, the polymer is a deoxyribonucleic acid (dna)

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