BLG 601 Lecture Notes - Lecture 14: Spermatocyte, Spermatogonium, Spermatid

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Spermatogonia are the cells that give rise to sperm cells. The spermatogonia divide by mitosis: one daughter cell remains a spermatogonium that can divide again by mitosis. The other daughter cell becomes a primary spermatocyte: the primary spermatocyte divides by meiosis to form secondary spermatocytes, the secondary spermatocytes divide by meiosis to form spermatids, the spermatids differentiate to form sperm cells. Sustentacular cells, in which the spermatogonia and developing sperm cells are embedded, maintain the blood-testis barrier. 28. 4 physiology of male reproduction: gnrh from the hypothalamus stimulates the secretion of lh and fsh from the anterior pituitary. Lh stimulates testosterone secretion from the interstitial cells. Inhibin has a negative-feedback effect on the anterior pituitary to reduce fsh secretion. Oogenesis and fertilization: oogonia give rise to oocytes, before birth, ogonia multiply by mitosis, during development of the fetus, many oogonia begin meiosis, but top in prophase i and are now called primary oocytes.

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