ENH 220 Lecture Notes - Lecture 11: Porphyrin, Hypochromic Anemia, Ferritin
Document Summary
Blood essential to transporting substances to tissues (o2/nutrients) & co2 & other waste products to excretory organs in the body: volume: 5 quarts (variable to individual, blood consists of cellular elements (in plasma viscous fluid) Stem cells: precursor cell in bm, differentiate to form red/white cells & platelets. Neutrophils: most numerous in adults w/ 70% of it as wbc, actively phagocytic, predominant in inflammatory reactions. Lymphocytes: 2nd most common in adults; predominant in children, may last for several years, location: lymph nodes, spleen, lymphoid tissues (& bm, par-take in: cell-mediated & humoral defense reactions. Normal hematopoiesis: hematopoiesis, formation + development of blood cells, bm replenishes bc, necessary substances required, 1. Combines w/ heme to form hemoglobin unit. Worn out rbc: removed from spleen, hg degraded & excreted as bile by liver, p. ring c/n be salvaged so globin chains broken down & used to make other proteins. Iron extracted & saved to make new hg.