FND 301 Lecture Notes - Lecture 5: Coronary Circulation, Blood Vessel, Atherosclerosis
12 Sep 2016
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Document Summary
Progression of atherosclerosis in coronary arteries is linked to decreased blood/oxygen ow to the heart muscle. Arteries contain fatty streaks (cholesterol & blood lipids) that have potential to become brous plaques. Development of fatty streaks begins in rst decade of life and in some, plaque formation can occur during adolescence. Most people have well developed plaques by 30 years old. Platelets: substances in blood that respond to injuries in blood vessels and important to blood clot formation. If clot formation exceeds the rate at which clots are dissolved, clots can stick to a plaque and close off a blood vessel (thrombosis) Coronary thrombosis: thrombosis of an artery that feeds the heart. Cerebral thrombosis: thrombosis of an artery that feeds the brain.
