BPK 375 Lecture 4: BPK 375 Week 5 Lecture 4 Notes
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Growth: is an increase in size without change in functionality. Maturation: involves a change in structure or function as the individual approaches the mature state. Hypertrophy: increase in cell size, hyperplasia: increase in the number of cells. Many tissues use both methods during the growth process. Prenatal and postnatal muscle development involves both hyperplasia and hypertrophy, while increase in muscle size occurs almost entirely via hypertrophy later in postnatal life. When a tissue undergoes hypertrophy, the increase can occur via auxetic (increase in cell size) or accretionary growth (increase in the extracellular constituents of the tissue) Height for weight is most basic measure of growth (figure 3-1), referred to a distance curve which shows the rate of growth in cm/years (distinct s-shaped pattern in the distance curve). Increase in the slope of the curve coincides with puberty or growth spurt (better depicted in the velocity curve). Evaluation of growth status requires comparison to normative data.