HSCI 100 Lecture Notes - Lecture 8: Bone Marrow, Blood Proteins, Haematopoiesis

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Lecture 8 hsci 100: transportation - oxygen, nutrients, wastes, co2, hormones, defense - distribute immune system components to destroy pathogens, regulatory function - body temp, ph, water-salt balance, blood is a fluid connective tissue. Formed elements: from cells produced in red bone marrow (45% of blood, red blood cells, white blood cells, platelets (cell fragments, mostly water) Plasma: fluid fraction (55% of blood, plasma proteins are most abundant organic molecules, many growth factors, hormones, signaling molecules, nutrients are transported in this fluid to sites throughout the body, capillaries are the sites for fluid exchange. Albumins - most abundant and important plasmas osmotic pressure as well as transport of other molecules. Globulins - important in transportation as carrier proteins: one class fights infection = gamma-globulins (or immunoglobulins or antibodies) Fibrinogen - important for formation of blood clots (or coagulation or thrombosis)

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