HSCI 212 Lecture Notes - Lecture 5: Innate Immune System, Tight Junction, Lysozyme
19 Oct 2015
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Lecture 5 quiz 2: epidemiology and immunology lectures (bring a calculator) immune system has primary and secondary organs. Long bones is where all the immune cells are born and produced and where they start out their development. Lymph nodes associated with many organs and tissues. Lymph nodes act as a meeting place for immune cells and potential pathogens. Immune system happens in stages (amount of infection and stages of immune response) Things that stop pathogens from entering our body (i. e. skin) Mechanical barriers: skin, tight junctions between epithelial cells (inside body, lining the gut), movement of fluid by cilia. Chemical fatty acids on skin, low ph in gut, enzymes (e. g. lysozyme in saliva), antibacterial peptides. Microbiological protection: symbiotic flora (bacteria that live in our gut that prevent other bacteria from growing) inflammatory response. Release of histamine (dilation of blood vessels) Antigen presentation to t-cells coming from antigens macrophage and b cells.
