MBB 231 Lecture Notes - Lecture 14: Enzyme, Hydrolysis, Organelle
9 Dec 2015
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Document Summary
During the process of translation, there are two major pathways for routing the newly forming polypeptide. The ribosomes are synthesizing polypeptides which are destined for the endomembrane system or for the export from the cell. These ribosomes become attached to the rough er membranes early in the translational process. The movement of the polypeptide across or into the er membrane is directly coupled with the. The ribosomes are synthesizing polypeptides which are destined for either the cytosol, These ribosomes remain free in the cytosol, unattached to any membrane. After translation has been completed, the polypeptides are released from the ribosomes and are. The signal hypothesis states that for a polypeptide to be destined for the endoplasmic reticulum, the n-terminus. Contains an er signal sequence which directs the ribosome-mrna-polypeptide complex to the surface of the. The er signal sequence does not initiate contact with the endoplasmic reticulum, instead the signal recognition.
