AN SC311 Lecture Notes - Lecture 10: Ketone Bodies, Ketosis, Pyruvic Acid

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Presence and absence of oxygen affects what we get out. How we get glucose out of muscle cells. Try to get more energy out of pyruvate. Measure co2 to see how much energy we get from the cycle. Total = 30 + 8 = 38 38 atp per molecule of glucose. Can get acetate from gut or a breakdown product. To cleave 2 carbon units off the main chain. Every time we remove 2 carbons the result is. Get more energy per amount of carbon from palmitate (fatty acid) Beta-oxidation is 1st step once you have free fatty acids (ffa) Inability to go from acetoacetate to acetoacetyl coa to 2 acetyl coa. Mobilize fatty acids to balance the -ve energy balance. Because of liver"s inability to oxidize fatty acids it turn into acetone. Know how they are made and why they are made. Ketone bodies are okay and can be used as energy outside of the liver.

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