BIOCH200 Lecture 27: BIOCHEM 200 - Lecture #27 - Glycolysis

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Glucose occupies a central position in the metabolism of most cells. Catabolic pathway: conversion of 1 molecule of glucose 2 molecules. Generates atp of pyruvate (3c) directly and nadh from oxidation of metabolites. Metabolism: contains important connections to intermediates to determine overall reaction rate, will mostly focus on the benefits of the skeletal muscle. The structures of glucose: glucose is the only aldehyde containing hexose. It is a six carbon compound with one aldehyde group and give hydroxyl groups. Glycolysis: a series of enzyme catalyzed reaction. 10 in total that occur in the cytosol: anaerobic pathway for atp generation. Does not have to operate under anaerobic conditions. One glucose broken down to 2 pyruvate. Stages of glycolysis: stage 1: energy investment. Energy in the form of atp is consumed. Involves the hexose sugars: stage 2: energy payout. Energy is harvested in the form of atp. Phases of glycolysis: each phase occurs 2 times.

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