BIOCH410 Lecture Notes - Lecture 9: G1 Phase, Bromodeoxyuridine, S Phase
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12 Feb 2020
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Received nutriton, building blocks to grow in size t be prepares to move to the synthesis (dna sin) phase. M: chromosomes separate to 2 daughter cells (identical) Important that both chromosomes are distributed properly. If chromosomal instability occurs, cancer can occur. Checkpoints ensure that di erent phases have been completed before they proceed. Those cells are metabolically active but not proliferating active. Growth factors let cells to transition from go to g1. Transition regulated through several proteins, tfs (phosphorylated retinoblastoma ?) control entry from g1 to s phase. Body will select the improper cells for apoptosis. Look at the amount of important biomolecules. Continuous growth in mass in terms of proteins. But mass of dna stayed content and only synthesized at s phase. Human cells complete the cell cycle in vitro in about a day. In vivo it can take unto 4 days. Septum: those cells populations have progressed through cytokinesis. Depending on the phase, the cells will use it.
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