MMI133 Lecture Notes - Lecture 1: Gram Staining, Mycology, Animal

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Course objectives: differences between microorganisms; how they cause disease (and why, how antimicrobials act to inhibit microbes, knowledge about the clinical conditions associated with infection, ramifications of epidemiology, spread and prevention of infection. Session objectives: introduction to microbiology, relative sizes of organisms, naming of bacteria based on their morphology, gram staining: how we differentiate bacteria. Influenza project: try to find a way to prevent replication of influenza by inhibiting the polymerase, which will target all types of influenza. 5 major categories of microbiology: bacteriology - study of bacteria, virology - study of viruses, mycology - study of fungi and yeast, parasitology - study of protozoa (amoeba, etc) and metazoa (worms) Immunology - study of immunity (resistance to infection) Smallest to largest: prions, virus, bacteria, fungi, parasites, mammals. Imbalance in bacterial flora due to previous treatment with antibiotics: virulence factors - infection with some strains of bacteria that causes them to damage tissue.

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