MICRB265 Lecture Notes - Lecture 13: Electron Transport Chain, Lipid Bilayer, Pseudomonas

• School: University of Alberta
• Department: Microbiology (Biological Sciences)
• Course: MICRB265
• Professor: Perrin Beatty

Document Summary

Thick layer of pg and no outer membrane, also has a think periplasmic space. Pg in gram positive cell wall form thick cables that wrap around cytoplasmic membrane providing shape, structure and rigidity. 90% of gram +ve cell wall is pg, rest is teichoic acids, lipoteichoic acids and proteins. Teichoic acids (acidic) bind divalent metal ions (e. g. ca 2+ and mg 2+) prior to transport. Lipoteichoic acids: teichoic acids covalently bound to membrane lipids. Teichoic = negatively charged but not attached to lipids. they are sticking out/ in pg. Important physiological differences between gram positive and gram negative bacteria. Gram positive more susceptible to b-lactam (penicillin-like) antibiotics and lysozyme. Gram positive in spore formation are more resistant to heat and mechanical stress. not all. Gram positive require additional vitamins or amino acids for growth. More susceptible to lysozyme activity than gram negative bacteria. Lysozyme and penicillin antibiotics can both inhibit peptidoglycan biosynthesis.