MMI133 Lecture Notes - Lecture 7: Tinea Cruris, Cryptococcus Neoformans, Lymphangitis

• School: University of Alberta
• Department: Medical Microbiology and Immunology
• Course: MMI133
• Professor: Judy Gnarpe

Document Summary

Id structures of fungi that can be used as targets for anti-fungal drugs. Define 3 types of fungal infections (superficial, cutaneous and systemic) and name common dermatophytic diseases. Define opportunistic, and give exps of opportunistic fungal infections. Important as nosocomial (hospital acquired) infections and as opportunistic infections of immunocompromised (increasing numbers today), few are primary pathogens. (cid:272)o(cid:374)ditio(cid:374)s ha(cid:448)e to (cid:271)e (cid:862)right(cid:863) for i(cid:374)fe(cid:272)tio(cid:374) to o(cid:272)(cid:272)ur; ie ca(cid:374)dida al(cid:271)i(cid:272)a(cid:374)s (cid:373)ay (cid:271)e o(cid:374) ski(cid:374) a(cid:374)d nothing will occur; but if get in a cut infection. Leavening agent for bread, fermentation for beer, wine, etc. Chitin stains with calcium binding agents- calcofluor white (stains white) - for rapid identification of fungi in clinical specimens; chitin = hard structure structural support. Ergosterol in cell membrane (we have cholesterol); leads to flexibility. Nystatin (usually applied topically, vaginally: moulds = has long hyphae (projections) Infected by spore turns into yeast in body. Important, b/c if have pt with thermally dimorphic, can not infect anyone else, b/c.