MMI133 Lecture Notes - Lecture 9: Staphylococcus Epidermidis, Gingival Sulcus, Cell Surface Receptor

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List the major components of the innate 1st line of defense. List and define the cell types involved in the 2nd line of defense. Describe the mechanisms involved in diapedesis, chemotaxis and phagocytosis. Identify the most important activated complement products and their biological activity. Explain how opsonization increases the efficiency of the immune system. Milkmaids who contracted cowpox were known to be immune to the more severe smallpox disease (cid:862)va(cid:272)(cid:272)ination(cid:863) In 1796, jenner successfully inoculated people with cowpox (vaccinia virus) to protect them against smallpox (variola virus) Recovery from some infectious diseases means protection later. Well balanced immune system should be able to: Ie lysozyme (breaks down peptidoglycan) can break down gram and + Fluid that flows into gingival crevice b/w teeth. Mucous membranes: thin and permeable barriers (line the respiratory, gastrointestinal, and genitourinary tracts) Ciliated cells in the respiratory tract (ciliary escalator) * = most abundant species in each site.

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