NURS 116 Lecture Notes - Lecture 4: Opportunistic Infection, Seroconversion, Subtypes Of Hiv

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State the virus responsible for aids and explain how it differs from most other viruses. Describe the mechanisms of hiv transmission and relate them to the need for public awareness and concern regarding spread of aids. Aids = disease caused by hiv infection; characterized by profound immunosuppression. Hiv transmitted through blood, semen, vaginal fluids, breast milk. Asymptomatic hiv infected people are still infections. Hiv = retrovirus; attacks cd4+ deteriorated is, Hiv-1 responsible for most infections worldwide; hiv-2 is endemic in w. africa, not so much other parts of world and don"t develop aids. Seroconversion- when infected person converts from being negative for hiv abs to being positive; occurs 1-3 mo after hiv exposure. Window pd- time after infection and before seroconversion; hiv ab results negative. Describe hiv structure and trace its entry and steps in replication within cd4+ Describe alterations in immune fxn that occurs in aids patients.

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