NUTR480 Lecture Notes - Lecture 7: Ferritin, Iron Supplement, Hematocrit

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goldleopard391

14 Mar 2017

School

University of Alberta

Department

Nutrition

Course

NUTR480

Professor

Heidi Bates

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Document Summary

Remember, without oxygen the metabolic production of energy to the muscles is compromised. Red blood cells (rbc) also called erythrocytes are responsible for delivering oxygen to the working muscles. Once they unload the oxygen the rbc carry co2 back to the lungs. The amount of oxygen that can be carried by the blood is proportional to the concentration of hemoglobin (hb) in rbc. This means that the athletes need to have adequate numbers of red blood cells and how much hb is in each rbc. Micronutrients are co-factors for the enzymes that form rbc and synthesize hb. The most important micronutrients in these processes are: iron, copper, folate, vitamin b12. Iron is a micronutrient that is needed in the production of both hemoglobin and myoglobin. Heme is an iron containing molecule at the center of each hb unit. It function is to bind oxygen and carbon dioxide reversibly. Myoglobin is an iron and oxygen binding protein found in muscle tissue.

Related Questions

Your patient is a married 47 year old white female homemaker with 2 children and an 18 year history of systemic lupus erythematosus (SLE). She has no known allergies. The pt takes an occasional naproxen for joint pain and antacid for heartburn but no other prescription or OTC (over the counter) medication. She neither smokes nor drinks alcohol (ETOH). Except for lupus, the patient's medical history is unremarkable. She is 5 feet 5 inches in height and weighs 102 pounds which is a decrease in weight of 23 pounds since her last physical examination nearly a year ago. She has had several small patches of hair loss on her head and her joints often hurt. Her ESR (erythrocyte sedimentation rate) is elevated at 70. She has a red rash on the sun exposed parts of her skin that looks like a vasculitis. She has 4 brothers and 3 sisters. An older sister has rheumatoid arthritis (RA) and an aunt with pernicious anemia and her deceased mother had Graves disease.

She had been aware of these problems for approximately four months. A physical examination was conducted during which her PCP noted multiple rash-like lesions on sun-exposed areas of the body, primarily on the arms and legs. A tissue biopsy of one of the lesions was taken and microscopic examination of the tissue revealed vasculitis (white blood cells within the walls of the blood vessels). An ANA test was positive. The lungs were clear to auscultation, heart sounds were normal with a prominent S1 and S2, and there was no evidence of enlarged lymph nodes. Blood tests revealed an Hct of 23% and an RBC count of 3.5 million/mm3. She was also jaundiced with some yellowing within the sclera. Microscopic examination of a peripheral blood smear revealed that red blood cells were normal in shape, size, and color, ruling out iron, folate, and vitamin B12 deficiencies. The total WBC count was 5,500/mm3 and her Plt count was 350, 000/mm3. Urinalysis was normal. She was placed on predisone for two months, during which time all signs and symptoms of disease resolved.

What can be said about the patientâs Hct, RBC count, WBC count, and Plt count?

byzantiumotter67

1. Anemia is the general term for conditions that result in theblood not being able to carry enough oxygen to the tissues in thebody. This can be due to a person's inability to produce enoughnormal hemoglobin molecules and/or red blood cells.

Which type of anemia is due to a decrease in red blood cellproduction because of a vitamin B12 deficiency?

Select one:

a. sickle cell anemia

b. pernicious anemia

c. iron-deficiency anemia

2. Which is the most common blood type in the US?

Select one:

a. A

b. B

c. AB

d. O

3. Which of the following is found in plasma?

Select one or more:

a. vitamins

b. red blood cells

c. hormones

d. platelets

e. all of the above

4. Cells that can differentiate into any of the formed elements(red blood cells, white blood cells, platelets) are celled Answercells

5. Eosinophils and monocytes are involved in allergicreactions.

Select one:

True

False

6. Hemoglobin is the molecule that floats around in blood andcarries oxygen molecules to the tissues in your body.

True or false: Oxygen binds to the iron in the hemoglobinmolecule.

Select one:

True

False

7. Hemolytic disease of the newborn can happen during a woman'sfirst pregnancy where the mother is Rh- and the fetus is Rh+.

Select one:

True

False

8. Leukemia is cancer of the white blood cell. It is the resultof an abnormal white blood cell multiplying uncontrollably. Why isit so letal? Because it takes over the red bone marrow and doesn'tallow normal red blood cells, white blood cells and platelets toform.

True or false:

Without enough red blood cells, you can't bring oxygen to thetissues in your body.

Without enough platelets, you won't be able to form clots, forinstance, to stop you from bleeding when you get a cut.

Without enough normal white blood cells, you cannot fightinfections properly.

Select one:

True

False

9. The neutrophil is the first white blood cell to arrive at thesite of an infection.

Select one:

True

False

10. Blood clots serve to stop a person from bleeding, forinstance, when they get a cut (a blood vessel is broken open). Whena blood clot forms in an unbroken blood vessel, it is called anembolus; when the embolus breaks free from the wall of that bloodvessel, it is called a thrombus.

Select one:

True

False

goldmallard347

11. Which of the following is an attribute of a scientifically literate person?

A. Creates templates for understanding

B. Constructs hypothetical arguments for discussion

C. Respects the rights of self determination

D. Uses scientific evidence to understand the natural world

E. Reports on social phenomena consistently

12. Which of the following does not contribute to the Calorie intake of a person?

A. Protein

B. Carbohydrate

C. Fat

D. Alcohol

E. Water

13. Which of the following is not a technique used to measure body composition?

A. Skin-fold calipers

B. Bod PodÃ

C. Body mass index

D. Hydrostatic weighing

E. Light absorption technique

14. Which of the following behavioral techniques supports healthy body weight changes?

A. Feasting

B. Fasting

C. Goal setting and a plan

D. Eating vegetables and meat

E. Regularly measuring body composition

15. The purpose of the warm-up is to:

A. Slowly increase the pulse rate to an aerobic level.

B. Facilitate vascular changes (splenic shunt) to accommodate aerobic exercise.

C. Gear up the energy metabolism, i.e., increase the delivery of oxygen and nutrients to the working muscle, and raise the temperature to an optimal level for energy production.

D. Increase the elasticity of the muscle fibers, which helps to prevent muscle, tendon, ligament, and joint injuries, as well as improve muscle contraction and preserve muscle glycogen in addition to reducing the amount of lactic acid build-up in the muscles.

E. All of the above

16. Which of the following reflects an improvement in cardiovascular health resulting from regular engagement in aerobic exercise?

A. Increased lean body mass

B. Increase in high-density lipoprotein cholesterol (HDL)

C. Stress relief

D. Improvement in sleep pattern

E. Reduced risk for developing certain types of cancer

17. The purpose of a cool-down is to:

A. slowly decrease pulse rate.

B. decrease core body temperature.

C. slowly constrict blood vessels.

D. continue adequate supply of blood to the brain, and facilitate removal of metabolic waste products from the muscles.

E. All of the above

18. A person trying to gain lean body mass has:

A. increased fluid needs.

B. decreased fat needs.

C. altered fitness needs.

D. increased protein and strength training needs.

E. decreased electrolyte needs.

19. Vitamin A in the form of _____ is used to treat acne.

A. retinol

B. retinal

C. retinoic acid

D. beta-carotene

E. lycopene

20. Which of the following is a genetic disease for which a low intake of copper is a component of treatment?

A. Pellagra

B. Wilsonâs disease

C. Hemochromatosis

D. Beriberi

E. Goiter

21. Which of the following nutrients is used to treat scurvy?

A. Folate

B. Riboflavin

C. Vitamin C

D. Niacin

E. Vitamin D

22. Which of the following groups is at highest risk for hemolytic anemia?

A. Premature infants

B. Elderly people who do not get exposure to sunlight

C. Pregnant women

D. Teenagers who do not drink enough water

E. Someone who does not consume animal meat or products

23. Iron deficiency causes:

A. microcytic normochromic anemia.

B. macrocytic hypochromic anemia.

C. microcytic hypochromic anemia.

D. macrocytic normochromic anemia.

E. macrocytic hyperchromic anemia.

24. Acrodermatitis enteropathica is caused by a deficiency of:

A. iron.

B. zinc.

C. chromium.

D. choline.

E. molybdenum.

25. Which of the following is required for the absorption of vitamin B₁₂?

A. A coenzyme

B. Intrinsic factor

C. Vitamin C

D. Bile acids

E. None of the above

26. Which nutrient potentiates the action of insulin?

A. Magnesium

B. Fluoride

C. Chromium

D. Selenium

E. Iodine

27. Which mineral is a central component of vitamin B₁₂?

A. Iron

B. Copper

C. Cobalt

D. Zinc

E. Molybdenum

28. Iodine is a component of:

A. hemoglobin.

B. myoglobin.

C. intrinsic factor.

D. insulin.

E. thyroxine.

29. Which of the following statements is not true regarding the diagnosis of a nutritional deficiency?

A. Dietary records should demonstrate low intake for that nutrient.

B. Blood levels should demonstrate high body levels of the nutrient.

C. Tissue levels should demonstrate low body levels of the nutrient.

D. Nutrient supplementation should correct the deficiency symptoms.

E. Clinical deficiency symptoms should be compatible with a low dietary intake.

30. Vitamin C helps maintain tissue integrity by:

A. neutralizing foreign proteins.

B. creating an alkaline cell environment.

C. recognizing cell boundaries.

D. forming collagen to bind cells together.

E. increasing inflammation

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NUTR480 Lecture Notes - Lecture 7: Ferritin, Iron Supplement, Hematocrit

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