PEDS101 Lecture Notes - Lecture 9: Sliding Filament Theory, Pearson Education, Autonomic Nervous System

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Muscles
Chapter 12a
Copyright © 2009 Pearson Education, Inc.
© 2013 Pearson Education, Inc.
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Overview
Part 1 Overview
Muscle types and functions
Part 2. Muscle structure
Ultrastructure
The
sarcomere
Copyright © 2009 Pearson Education, Inc.
The
sarcomere
Contractile proteins
Part 3. Excitation-contraction coupling
Molecular basis of contraction
Sliding filament theory
Role of calcium and ATP
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Nucleus
Muscle fiber
(cell)
Striations
Skeletal muscle fibers are large,
multinucleate cells that appear
striped or striated under the
microscope.
Part 1. Overview- three types of muscle
Nucleus
Muscle fiber
Intercalated
Cardiac muscle fibers are also
striated but they are smaller,
branched, and uninucleate. Cells
are joined in series by junctions
called intercalated disks.
attached to and moves bones
regulated by somatic n.s.
nervous system
pumps blood
Copyright © 2009 Pearson Education, Inc.
Intercalated
disk
Striations
Nucleus
Muscle fiber
Smooth muscle fibers are small
and lack striations.
pumps blood
regulated by autonomic
nervous system and chemical
signals (e.g. hormones)
surrounds organs/vessels
regulated by autonomic
nervous system and chemical
signals (e.g. hormones)
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Document Summary

Skeletal muscle fibers are large, multinucleate cells that appear striped or striated under the microscope: attached to and moves bones, regulated by somatic n. s. nervous system. Cardiac muscle fibers are also striated but they are smaller, branched, and uninucleate. Cells are joined in series by junctions called intercalated disks: pumps blood, pumps blood, regulated by autonomic nervous system and chemical signals (e. g. hormones) Smooth muscle fibers are small and lack striations: surrounds organs/vessels, regulated by autonomic nervous system and chemical signals (e. g. hormones) For smooth and cardiac muscle, there is antagonistic control. A group of muscle fibres bundled together in connective tissue is a muscle fascicle. Sarcolemma- muscle fibre membrane, carries action potential along muscle fibre. Thick and thin filaments contract and slide together and is what allows for contacting of each myofibril. A single muscle cell is a multinucleated muscle fibre that contains many myofibrils (b) T-tubules- carry action potentials deep into muscle fibre.

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