PEDS200 Lecture : Hormones-2
17 Dec 2011
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Document Summary
Influence gene expression & synthesis of intracellular proteins: testosterone can enter nucleus of muscle cell and alter genetic expression of muscle proteins. Anabolic steroids: synthetically produced, mimic anabolic properties of endogenous steroid hormones: liver toxicity, elevated blood pressure, elevated cholesterol and triglycerides, decreased hdl (can cause heart attacks, depressed spermatogenesis, lowered testosterone production, masculinization, lowered voice in women and children, clitoral enlargement in women, increased aggressiveness. Influence other physiological responses: exercise-induced incr. in cortisol, released from adrenal cortex suppress various immune cells. Open window hypothesis: post exercise immune suppression leads to time when athlete is more susceptible to infections. Protein turnover: protein degradation/synthesis with in tissue, constant process necessary for repair & building. Relative balance between anabolic and catabolic hormones determine net results in: How does exercise help reduce insulin resistance of tissue:
