PHYSL210A Lecture Notes - Lecture 7: Esophagus, Stomach, Intestinal Epithelium

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Gastrointestinal tract physiology: general introduction to the gastrointestinal system. Transfers digested organic nutrients, minerals and water from the external environment to the internal environment (on the other side of intestine: digestion. Chemical alteration of food into absorbable molecules (through multiple molecules) Gi motility (smooth muscle contraction), ph changes (acid breakdown), biological detergents (produced by liver) and enzymes (produced by liver: absorption. Movement of digested food from the intestine into the blood or lymphatic system. Non-absorbable components of food, bacteria, intestinal cells, hydrophobic molecules (drugs, cholesterol, steroids) All these pass right through digestive system psyco. Host defense: git is continuous with the exterior of the body. Skin outside, center of donut so is continuous with exterior of system. Potential portal for harmful substances and microorganisms: highly developed immune system. Components of the git: mouth, pharynx, esophagus, stomach, small intestine, duodenum, jejunum, ileum, large intestine = tract, accessory organs = pancreas, liver, gall bladder.

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