CMMB 403 Lecture Notes - Lecture 11: Polymerase Chain Reaction, Sox3, Y Chromosome
Document Summary
Sry did not appear until about 200 mya. Platypus is an egg-laying mammal and doesn"t have sry. Other animals have a variety of means (having sox genes, not necessarily sry) of determining sex. During evolution, sry gene only appeared about 200 mya, and seemed to have evolved from sox3 gene. 2 autosomes become sex chromosomes, each had sox3 gene, and now all of us have sox3 on our x chromosome, the other autosome that becomes the y also had a sox3 but that. Sry is in a dangerous location in humans xy females are relatively easy to. In mice, sry is at the other end of the y chromosome. Sry was found by searching for what gene is gained (translocated to another chromosome) in xx males, and by looking for what gene was lost or mutated in xy females. Sry is located in a dangerous location.