ANSC 3080 Lecture Notes - Lecture 5: Mesonephric Duct, Paramesonephric Duct, Rete Testis
Document Summary
What is sex: need for 2 individuals: produce germ cells which fuse to produce an offspring, difference (sexual dimorphism) carried by genes = sex chromosomes (mammals: xx=f, xy=m; birds: zw=f, zz=m, during early fetal life, gonads are undifferentiated. Formation of primordial germ cells (cid:523)p. g. c. "s(cid:524: differentiation of cortex into ovary or medulla into testis testis organization through transient expression of genes (testes differentiation factor - tdf) from the sry (sex-determining region y) Colonize the genital ridge to form indifferent gonads. Coelomic epithelium sertoli cells (produce mis: mesonephric mesenchyme connective tissue (tunica albuginae), blood vessels, leydig cells (produce testosterone, testosterone stimulates the development of the mesonephric duct. Development of the ovary: absence of mis: development of paramesonephric duct female tract forming a rudimentary rete. Development of the: absence of testosterone: regression of mesonephric duct, coelomic epithelium will form the cortex, second generation of cord epithelium form primordial follicle, mesonephric tubules regress to form a rudimentary rete.
