ANSC 3080 Lecture Notes - Lecture 12: Vascular Resistance, Angiotensin, Proximal Tubule
27 Mar 2018
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Document Summary
Kidneys receive blood directly from the aorta, getting large amount of blood (high perfusion) Composition and volume of body fluids must remain constant (blood, extracellular fluid) Urinary system with the kidneys is the primary regulator of volume and ion (na and k) concentration in extracellular fluid. Selective excretion (not just simple diffusion): important products retained (glucose, aa, proteins), waste removed. Excrete body organic wastes: urea (metabolism of proteins), bile (degradation of hemoglobin . Stabilize osmolarity (volume and the concentration of ions in extracellular fluid) Remove wastes and foreign substances from the blood. Contribute to the acid balance by removing h+ and bicarbonate (hco3-) Similar to the lungs (both at the interface of blood and outside environment) Produce erythropoietin to stimulate the formation of erythrocytes. Produce calcitriol = active form of vit d. Produce renin, an enzyme that regulates the formation of angiotensin ii (regulates blood pressure and aldosterone) Kidneys are located on the upper abdominal wall.
