ANSC 3180 Lecture Notes - Lecture 17: Granulosa Cell, Ovarian Reserve, Oocyte

• School: University of Guelph
• Department: Animal Science
• Course: ANSC 3180
• Professor: Esther Finegan

Document Summary

Formation and development of ovarian follicles, which are endocrine structures that participate in the coordination of reproductive cycles and support the development of the female germ cell (oocyte) Protracted process that encompasses the differentiation and release of a mature oocyte for fertilization and successful propagation of the species. Oogenesis begins during embryonic development of the female and continues throughout her reproductive lifetime. Oocyte is not capable of synthesizing cholesterol from acetate. Granulosa convert acetate to chole, transfer to oocyte. Oocyte does not have transporter for alanine. Granulosa uptake alanine and transfer to oocyte. Oocyte not efficient to convert glc to pyruvate. Granulosa synthesize pyruvate and send them to oocyte for generation of atp. Oocyte secretes a lot of factors that determines the process of follicular cells. Small gtpase, bring chromosome to one side of the oocyte (eccentric positioning of meiotic spindles)