BIOC 2580 Lecture Notes - Lecture 14: Gerty Cori, Lactate Dehydrogenase, Cori Cycle

57 views2 pages

Document Summary

Pyruvate further metabolized via 1 of 3 routes depending on prevailing physiological condition. Carry out glycolysis as on going process conditions. Nadh produced in glycolysis (g3pdh) must be re-oxidized. Nadh generated in glycolysis cannot be oxidized via etc. Tissues switch to using pyruvate itself to re-oxidize nadh ferent ons. nds. Via lactate dehydrogenase regenerating the nad+ necessary for glycolysis. Strenuous exercise recovery lactate exported from muscles to blood, Blood liver, liver recycles lactate via converting back to glucose = gluconeogenesis. Liver can subsequently export the glucose back to the muscles. This exchange of metabolites btw the organs = cori cycle (carl and gerti cori) Nad+ regenerated via these reactions allowing glycolysis to continue under anaerobic conditions. **alcohol dehydrogenase found in many organisms (including humans) Aerobic conditions ~ metabolism of pyruvate and nadh. Nadh (from g3p dehase) is oxidized via the mitochondrial etc. Pyruvate oxidized acetyl coa completely oxidized to co2 via the tca cycle.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents

Related Questions