BIOM 2000 Lecture Notes - Lecture 21: Distal Convoluted Tubule, Proximal Tubule, Ultrafiltration (Renal)

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The peritubular capillaries reabsorb useful substances (water, glucose, amino acids, ions) Most reabsorption occurs in the proximal convoluted tubule. Materials not absorbed: nitrogenous waste products (urea, uric acid and creatinine) Some materials move from the blood of the peritubular capillaries into the renal tubules (hydrogen and potassium ions and creatinine) Process is important for getting rid of substances not ready in filtrate. Materials left in renal tubule move toward the ureter. In 24 hours, 1-1. 8 litres of urine are produced. Filtrate contains everything that blood plasma does (not proteins) Urine is what remains after the filtrate has lost most of its water, nutrients and necessary ions through reabsorption. Urine contains nitrogenous wastes and substances that aren"t needed. Yellow due to pigment urochrome (destruction of haemoglobin) and solutes. Normal solutes: sodium/potassium ions, urea, uric acid, creatinine, ammonia, bicarbonate ions. Abnormal solutes: glucose, blood proteins, rbcs, hb, wbcs, bile.

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