NUTR 1010 Lecture Notes - Lecture 12: Mediterranean Diet, Olive Oil, Safflower
27 Feb 2017
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Main cause = atherosclerosis: plaque development in arteries, top left: normal artery, lumen is completely open, top middle: when plaque develops there is a. Response to injury due to high cholesterol levels in the blood, excess glucose in diet, genetic related, due to chemicals (smoking), ldl fat cells become oxidized in the artery lumen. That oxidation triggers an immune response which is why the macrophage (large white blood cell) start to enter the lumen. Macrophages have scavenger receptors that attract more ldl cholesterol: 3. fatty acid cells start to form plaque in the artery, 3. Fats and heart disease: saturated and trans fats increase risk of heart disease, omega-3 and omega-6 polyunsaturated fats decrease risk, how?, they effect the type and amount of lipoproteins, triglycerides, and cholesterol in the blood. What are lipoproteins: carriers of lipids within the blood, fat packaged into lipoproteins to travel through body. What are lipoproteins: chylomicron get broken down into vldl, ldl and.
