PATH 3610 Lecture Notes - Lecture 1: Ethylene Glycol Poisoning, Acute Tubular Necrosis, Nephron
28 Sep 2017
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Document Summary
In the unit on inflammation, we discussed the outcomes of acute inflammation. Resolution (the ideal outcome) refers to the return to normal which will follow an uncomplicated acute inflammation. The tissue is restored to its original state, prior to the injury. If tissue damage was more extensive, some degree of regeneration (the replacement of necrotic parenchymal cells by new parenchymal cells of the same type), scarring, or a combination of the two may result from acute inflammation. Finally, we discussed abscess formation and its possible outcomes. In chronic inflammation, there has been considerably more tissue injury, so true resolution cannot really occur. Concurrently, the necrotic cells and inflammatory debris must be removed. Read the overview of tissue repair" in your textbook, found on p. 58. It occurs by 2 types of reactions: regeneration of the injured tissue and scar formation by the deposition of connective tissue: regeneration:
