PSYC 2330 Lecture Notes - Lecture 11: Limbic System, Cue Reactivity, Conditioned Place Preference

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Direct conditioning: very selective of when stimuli are presented, conditioning of a-process. Drug-like responses = similar to acute effects: conditioning of b-process. Drug-opposite responses = similar to withdrawal: dr. shirley spragg in chimpanzees. Conditioned place preference (cid:862)needle freaks(cid:863: people who like to inject themselves, even if there is no drug. Chimps will lead experimenter to the room to receive injections. Room is seen as incentive stimulus: a-process: positive emotional reaction. Goldberg and schuster (1970) in morphine-dependent monkeys. O"brie(cid:374) et al. (cid:894)1977(cid:895) i(cid:374) (cid:373)ethado(cid:374)e depe(cid:374)de(cid:374)t hu(cid:373)a(cid:374)s. Changes in affective reactions to drug cues ((extinction in needle freaks) Tolerance can result from compensatory crs, and can be context-dependent: decrease in salivation caused by decaf. Increases in alcohol intoxication when drinking green beer: decreases in alcohol intoxication when drinking in a bar. Increases in heroin over-dosing when injections given in unfamiliar environments. Cue-reactivity: autonomic arousal, skin temperature and conductance heart rate, blood pressure.

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