BGEN 3020 Lecture Notes - Lecture 5: Esophageal Cancer, Stratum Corneum, Cholangiocarcinoma

• School: University of Manitoba
• Department: Biochem. and Medical Genetics
• Course: BGEN 3020
• Professor: Jason Leboe- Mcgowan

Document Summary

Atrophy: diagnosis: the decrease in tissue mass and the cell decreases in size. Question can be asked what kind of growth alteration can occur here. The fasiculata is where glucocorticoids (cortisol) are made, while reticularis is where sex hormones are made (17 ketosteroids and testosterone). Acth is responsible for stimulating these, therefore zona fasiculata and zona reticularis are atrophied: taking thyroid hormone will lead to atrophy of thyroid gland. Tsh and therefore nothing is stimulating the thyroid gland which leads to atrophy: example: slide showing a biopsy of a pancreas in a patient with cystic fibrosis. Atrophy, b/c the cftr regulator on c"some 7 is defective and has problems with secretions. In the other kidney, it is overworked, therefore there is hypertrophy (renin level coming out of this vein is decreased and suppressed). Hypertrophy increase of the size of cell, not number. Hypertrophy of a cardiac muscle (permanent muscle), suppose there is a block just before the g2 phase.