BIOL 2420 Lecture Notes - Lecture 34: Abo Blood Group System, Gamma Globulin, Mast Cell

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Igm: primary antibody against a & b antigens on red blood cells. Igg: 75% of all plasma antibodies in adults. Maternal iggs cross placental membrane and gives newborns immunity ( rst 6 month) Igg and igm: produce most speci c immune response against bacterial invaders and some viruses. Antibody mediator to allergic response, ex. hay fever, asthma. Iga: found in secretions of digestive, respiratory, genitourinary systems, tears, breastmilk, sweat. Igd: found on surface of b-cells, function rather unknown. Tcrs and bcrs are all made randomly. Antigen recognition leads to an immune response. T-cell and b-cell maturation involves a test. Rh antibodies belong to igg class -> do cross placenta barrier. Rh+ = d marker present on rbc, rh- = d marker not present. Infectious particles made up of nucleic acid (dna or rna) & protein. Host cell machinery for their own reproduction.

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