MBIO 1010 Lecture Notes - Lecture 22: Adaptive Immune System, Antigen-Presenting Cell, Reactive Oxygen Species
8 May 2017
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Document Summary
Activated phagocytes produce reactive oxygen compounds: o. Neutrophils perform exocytosis components once invaders have been killed: Macrophages and dendritic cells become antigen presenting cells . Fragments of the intruder are presented on the cell surface to trigger an adaptive immune response. Five cardinal signs: redness, warmth, pain, swelling and loss of function reaction to. In response to infection, injured tissue and leukocytes release proinflammatory cytokines. Temperature increase may slow the growth of pathogens . Acquired when a pathogen is encountered for the first time . Has memory: : responds more vigorously the second time a particular pathogen is encountered. Glycoproteins composed of 4 subunits: 2 identical heavy chains , 2 identical light chains. Each antibody has 2 identical antigen binding sits (fab) . And one fc site can interact with other components of the immune system . First antibody made when a new antigen is encountered .
