MBIO 2370 Lecture Notes - Lecture 4: Electron Acceptor, Cytochrome C Oxidase, Nadh Dehydrogenase

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Summary so far - glycolysis --> pyruvate --> acetyl coa --> tca cycle: these processes generate little energy as aap. But do generate reduced electron carriers - nadh and fadh2. In aerobic cells, these oxidized via a series of oxidations and reductions terminating with o2 which generates most of the energy used for atp synthesis - oxidative phosphorylation. Intermediates in this series constitute the electron transport chain. Also known as the respiratory chain: forms part of the inner mitochondrial membrane and together with the enzyme that generates atp from adp is approx. The transport of electrons from nadh to o2 is a multi step process and coupled to atp formation (oxidative phosphorylation) The electrons are carried through a series of proteins in the inner mitochondrial membrane where. O2 serves as the terminal electron acceptor to form h2o: series of oxidation reduction reactions, the electrons are not free floating. They are passing from molecule to molecule.

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