MBIO 3010 Lecture Notes - Lecture 29: Immunoglobulin A, Cranial Nerves, Cervical Cancer
28 Dec 2016
School
Department
Course
Professor
Document Summary
Morphology where they have a halo around the nucleus. 16 and 18 are the most common causes of cancer. 6 and 11 are known to cause anorectal warts in males. Contains rna - must convert rna to dna by reverse transcriptase. Having rna means it can mutate much faster - prevention is impossible. B most common in na and europe. Increased travel is causing a change in the subtype distribution. Binding of viral gp120 envelope glycoprotein to cd4 receptor. Individuals with ccr5 gene deletions - resistant. Disease progression seen with hiv variants using cxcr4 receptors. Viral replication halts after integration of provirus. In resource rich countries sex is the common method of transmission. In resource poor countries sex and mother to baby are very common. 20% infants infected in utero and intrapartum. Associated with breastfeeding for up to 24 months. Cd4 + count, 200/mm^3 (>1000mm^3 - normal value)
