MCIM 224 Lecture Notes - Lecture 14: Macrophage, Fever, Corticosteroid
Document Summary
Create a physical / biological / chemical barrier that prevents foreign material from entering internal (sterile) body sites. Distinguish that which is foreign to the body ( non-self) from that which is self (& eliminate the foreign stuff) Create a memory of previously encountered foreign material so that a later exposure gives a faster, stronger response. Defense requires ability to recognize and eliminate acting as virus host a self cell. Defense requires ability to recognize and eliminate microbe (while not harming host tissues) a non-self . Use multiple mechanisms that cooperate with one another, and (redundancy). back each other up. Defense against foreign microbes occurs via two mechanisms: Respond the same way regardless of the type of microbe. No memory (repeated exposure doesn"t make response better) An individual response designed for each different microbe. Memory (a second exposure to the same microbe gives a faster response) and stronger.