BIOL130 Lecture Notes - Lecture 3: Phosphodiester Bond, Pentose, Polymerization

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Information stored as dna enables living organisms to pass on hereditary information. Also allows each cell to pass on hereditary information to next generation of cells. Sequence of subunits in dna polymer directs rna synthesis. Phosphate + deoxyribose + base (a, c, g or t) datp damp, dgtp, dntp. Rna directs ordering of aas in a peptide chain. Phosphate + ribose + base (a, x, g, or u) Nucleic acids are linear (unbranched) polymers of nucleotides. Each nucleotides consists of three parts: a nitrogenous base, a pentose sugar, a phosphate group. Ribose + base + phosphate = nucleotide: atp = nucleoside triphosphate. Agents in energy transfer reactions: cleave off phosphate group to release stored energy. Atp adp + pi + energy. Ntp ndp + pi + energy. Phosphodiester linkage forms between 5" and 3" carbon. Read from 5" to 3" 5" actgc 3" goes with 5" gcagt 3".

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