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BIOL 239 (290)

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BIOL 239
Christine Dupont

Set 132 TranscriptionThe process by which the polymerization of ribonucleotides guided by complementary base pairing produces an RNA transcript of a genelike we saw from DNA replication its going to use a polymerase but its RNA this time Still adds nucleotides to 3 5 to 3 is a rule for polymerasesNucleotides are added in the 5 to 3 directionUracil is incorporated in place of thymine in RNA both pair with adenine3 TranscriptionRNA polymerasethe enzyme that catalyzes transcriptionjust like for translation stop and start codon methioninethere are places to start and stop transcription but theyre not codons because were not making protein were making mRNAplaces to begin transcription are promoters Large sequences of DNAtheyre the place where polymerase recognizes and comes inPromotersDNA sequences near the beginnings of genes that signal RNA polymerase where to begin transcriptionmakes the transcript and stops not at the codon but at the terminator large sequence of DNA againTerminatorssequences in the RNA products that tell RNA polymerase where to stop encoded by DNA polymerase falls off and releases transcript the mRNAit gets translated from here so now start and stop codons kick in4 The steps in transcription Ecoli 5 The steps in transcription Ecoli6 The steps in transcription Ecoli
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