BIOL303 Lecture Notes - Lecture 4: Zona Pellucida, Ovarian Follicle, Chemotaxis

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Sperm: male gamete that contains a haploid nucleus. Acrosome: modi ed golgi secretory vesicle that contains enzymes and complex sugars. Capacitation: the nal maturation of mammalian sperm that occurs in the female reproductive tract. Includes post translational modi cations of sperm that make cell membrane potential, more negative, remove cholesterol, move the acrosome closer to the membrane surface and changes location of receptors. Egg/ovum: female gamete that contains a haploid nucleus. State of ovum at fertilization depends on species. Mammalian ovum are in dicytotene (metaphase 1 arrest) and resume meiosis upon hormonal stimulation before ovulation. Oocyte: developing ovum that is not able to bind sperm or be fertilized. Dicytotene: resting phase of primary oocytes in mitosis. Vitelline membrane: thin tough ecm layer found in invertebrates. Zona pellucida: thick ecm layer found in vertebrates. Cumulus: layer of ovarian follicle cells surrounding the zona pellucida.

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