BIOL303 Lecture Notes - Lecture 2: Ian Wilmut, Cell Nucleus, Somatic Cell
Document Summary
Key concepts & study questions for biol 303. Genomic equivalence: the theory that every cell of an organism carries the same genome. The tail of histone 3 and 4 can be modified and the modification of histone can change the state of the chromatin. Depending on which lysine residue is being methylated and other nearby methylation or acetylation, its effect can be either repressive or activate, but generally repress gene expression: some proteins can specifically bind to methylated lysine on histone. H3 and can function either active or repress gene expression: 4, All transcription factor has the ability to bind dna and influence gene transcription in doing so. They bind to very specific sequences on the. Dna that will then enhance or suppress the ability of rna polymerase to initiate transcription at nearby promoter. Enhancers may bind several transcription factors, and gene transcription is often controlled by specific combinations of transcription factors.